Since 1968, when the New England Journal of Medicine editors precipitously and unfairly saddled adverse reactions of some people to Monosodium glutamate (MSG) with the name Chinese Restaurant Syndrome, MSG has been stigmatized as a food additive that is apart from and somehow unhealthier than other food additives. The first person to report symptoms to the Journal was a Chinese-American doctor, Robert Ho Man Kwok, who complained of numbness at the back of his neck, general weakness, and heart palpitations after eating at a Chinese restaurant. On this slim testimony and that of several others, the Journal coined the phrase Chinese Restaurant Syndrome.
A type of kelp known as Dasima in Korea, and Kombu in Japan, is a key ingredient in Dashi, a broth from which Japanese professor Kikunae Ikeda identified the quality of umami in 1908 that led him to the discovery and production of MSG. Photo by freddy an.
Use of MSG is not limited to Chinese cookery, however, and it can be found in many processed American foods such as Doritos, which millions of Americans appear to consume regularly without complaint. It would be interesting to see if more people would attest to adverse reactions to eating Doritos if they were made aware the product contained MSG. It is listed among the ingredients on the package, and using its most recognizable name, too, rather than one of the many names that can hide its presence, such as autolyzed yeast.
This is not to say no one can have a real adverse or allergic reaction to MSG. But for just about any ingredient in food there are some people who react badly to ingesting it. The main thing to remember is that in scientific studies of MSG, as opposed to the purely anecdotal stories that appeared to satisfy the editors of the New England Journal of Medicine in 1968, no one has found that MSG is any more dangerous than any of a multitude of other food additives. If it were as dangerous as some people appear to believe it is, not only would the Food and Drug Administration (FDA) likely take it off its generally recognized as safe (GRAS) list, but thousands or even millions of Asians and Asian-Americans would be suffering every day from its effects.
Yet Asian chefs and home cooks continue to add MSG to their meals. They are either perverse in their determination to eat the possibly unwholesome ingredient, or they are unconvinced by the nearly hysterical denunciations of it coming from some people in North America and Europe. Given the ubiquity of MSG in highly processed foods that Americans eat and enjoy every day, any real or imagined adverse reaction to it could just as easily be called American Junk Food Syndrome. There is already one name for that, which is Obesity. American food processors discovered around the time of World War II that MSG was a useful flavor booster for otherwise bland or even flavorless foods like canned vegetables and corn snacks. MSG by itself does not encourage obesity, but its overuse in helping to make some rather unpalatable and non nutritious foods delicious does contribute to obesity.
Shavings of Katsuobushi, a preserved and fermented skipjack tuna used in Dashi, the umami broth from which Professor Ikeda first isolated MSG. Photo by Sakurai Midori.
At the same time as food scientists and agribusinesses were discovering how to make cheaply made, highly profitable junk food flavorful, they were also inadvertently taking the flavor out of healthful foods by manipulating them to improve qualities like pest resistance, standing up to shipping, or tolerating being confined on factory farms, all at the expense of flavor and nutrition. Those practices yielded bland, watery supermarket produce, and meats needing seasoning and breading and all sorts of treatments in order to taste like much of anything. It’s not all that mysterious why shoppers, particularly poor ones who can’t afford to seek out higher quality ingredients, turn to highly processed, highly flavorful foods, even at the cost of poor nutrition and cumulative destructive effects on their health.
In this country, people like to blame the victim. After all, free enterprise and free choice means people don’t have to eat junk, doesn’t it? It’s also useful to have an Other to blame, as in Chinese Restaurant Syndrome. The sensible thing would be to teach children in schools about moderation in all things, including sprinkling additives on their food. A little bit of MSG on already healthful food gives an umami flavor boost and has not been shown to do harm to the great majority of people who eat it that way. MSG put on every unwholesome, processed food cannot be healthy since the bad effects of poor quality food combine with excessive amounts of this otherwise relatively harmless additive. Enormous amounts of any additive are probably not healthy, not just MSG. School administrators could stress in the curriculum healthful eating instead of allowing vending machines full of snacks, sodas, and sugary fruit drinks in the hallways. In the case of young people at least, free enterprise and free choice should take a back seat to learning healthy habits.
— Izzy
“Gobbledygook” has three syllables, making it a suitable candidate for the brand name for a drug since they often have names that length, names such as Cosentyx and Myrbetriq. “Gobbledygook” doesn’t have any rarely used consonants, however, consonants such as “x” and “q” and “z”. Marketers also like to end their invented words for products with a vowel such as “a” or “o”, a practice they have followed with automobiles as well as drugs, as in Elantra, Levitra, and Toronado and Lexapro. Are they cars? Are they drugs? Manufacturers and their marketers spend millions of dollars to persuade prospective customers to feel good about their products and to feel they are unique, but it all ends up muddled together as gobbledygook.
George Larrick was the last investigator to rise through the ranks to become Commissioner (1954-1965) of the Food and Drug Administration. Inspector Larrick assembled an exhibit of dubious and even dangerous food and drug products, dubbed by reporters an “American Chamber of Horrors”, which effectively documented the need for what became the 1938 Food, Drug, and Cosmetic Act. Photo from the Food and Drug Administration.
The pharmaceutical companies are under much greater restraints in product naming than the automobile manufacturers, who apparently invent their names merely from the results of market research and internal spitballing. All those names ending in vowels, a fairly rare occurrence in English, but more common in the Romance languages such as Spanish, may be intended by automobile marketers to make buyers feel they are getting something faintly exotic. Drug makers have to submit brand names of new products to the Food and Drug Administration (FDA), which has rules to ensure drug names are sufficiently distinct from one another to minimize the risk of confusion which, in the case of drugs, could lead to serious complications or death for patients if doctors or pharmacists mistakenly substitute prescriptions. There is no comparable risk involved in driving an Elantra instead of a Celica.
Using a drug’s scientific name is not an option the drug companies seriously consider because those names are often more polysyllabic and unpronounceable than the silly brand names they ultimately invent. In a very few instances, a shortened form of the scientific name becomes generally recognizable, as in ibuprofen or acetaminophen, but those can’t be trademarked. Therefore we have the option of buying Advil or generic ibuprofen, Tylenol or generic acetaminophen. It’s no accident, by the way, that both of those brand names are simpler and easier to pronounce than more recent drug brand names, since both of them were developed over thirty years ago, when competition in the pharmaceutical market hadn’t heated up to today’s incandescent level.
What has changed since then has been the increasing average age of the population and the consequent increase in demand for medicines to treat their growing health complaints. Drug manufacturers are also not above boosting demand with lengthy and frequently repeated television commercials urging prospective users to pressure their doctors into prescribing the advertised medicine. They cover the other end as well by sponsoring junkets and giveaways for doctors, nudging them toward prescribing the latest drug they have developed.
A most excellent reading by Irene Worth and John Gielgud in 1983 of T.S. Eliot’s Old Possum’s Book of Practical Cats. The entire book is presented in this video, but the part that concerns us here is the first poem, “The Naming of Cats”, which proceeds up to the 1:45 mark.
It’s a high stakes game for pharmaceutical companies that have spent millions of dollars on research and development for a drug, and then millions more on shepherding it through FDA approval, and finally marketing it. Notice how television drug ads are 60 seconds long instead of the usual 30 seconds, and how often they are repeated, particularly during the day when their target audience of older people are presumably at home watching. There’s gold in them thar hills of retirement, and pharmaceutical companies mean to get their share. Whether the residents of the golden hills are better off with the latest heavily advertised gobbledygook drug or something else, or with nothing at all, is up to them and not to marketers, no matter how warm and fuzzy the television ads portray their lives can be, to paraphrase the Rolling Stones “(I Can’t Get No) Satisfaction”, an old song the human targets of drug ads might still remember well.
— Ed.
Cannabidiol (CBD) oil has been showing up on the shelves of pharmacies, grocery stores, and health food outlets around the country over the past few years, and yet there remains some confusion about the legality of the product. CBD oil is derived from the Cannabis sativa plant, the same plant that produces hemp and hemp-derived products, as well as marijuana and all its psychoactive derivatives. The difference between hemp and marijuana is in the strain, or variety, with plants bred for hemp production being much lower in the psychoactive property of marijuana known as tetrahydrocannabinol (THC). CBD oil is typically very low in THC, often less than 0.03%, sometimes 0%, and the easiest way for manufacturers to keep THC content low in their CBD oil is to produce it from hemp plants, which are naturally deficient in THC but flush with cannabidiol.
Cannabis sativa plants growing in the Botanical Garden at Karlsruhe, Germany, in August 2009. Photo by H. Zell.
Many users and manufacturers have been touting the benefits of CBD oil for treating epileptic seizures, inflammation, and arthritic conditions, among other conditions. People are eager to use the product, but the Drug Enforcement Agency (DEA) has been holding up progress because they classify anything even remotely connected with marijuana as a controlled substance, and therefore illegal. The DEA has rules defining what is marijuana and what is not which are byzantine in their complexity and which can conveniently be applied at their discretion. Meanwhile, states have been passing laws, not just rules, related to marijuana and hemp products, and some of those laws contradict DEA rules. Do the mere guidelines of a federal agency supersede state laws? In a manner of speaking, that’s no way to run a railroad.
Congress needs to pass legislationrestricting the reach of the DEA so that it is not constantly in conflict with state laws and causing confusion among the citizenry. Like any bureaucratic agency, the DEA will fight to maintain its budget and its relevance. Congress must drastically curtail the DEA’s mission, however, because the agency has long overstayed its welcome as society has moved on. Over the long term, the DEA and the regulations it enforces have had the same deleterious effect on society as Prohibition and Prohibition agents in the early twentieth century. The peculiar thing about the foggy legal status of CBD oil caused by the DEA standing in the way of progress the states are trying to make is that the Food and Drug Administration (FDA) is having a difficult time regulating the CBD oil market because of its status in limbo. Any policy that continues on the books after it has lost the support of the populace needs to be eliminated before it becomes subject to abuse by an irrelevant agency seeking to hold onto power using selective enforcement on behalf of its own entrenched bureaucratic interests and those of powerful pharmaceutical companies.
— Izzy
Male flowers of a Cannabis sativa plant growing in the Botanical Garden at Karlsruhe, Germany, in August 2009. Photo by H. Zell.
